The Opportunity For Cannabinoid Medicines

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Of Clinical Trials

CATE Trials – Investigating MRX2 & MRX2T for Refractory Epilepsies

Epilepsy
UCL
GOSH
NIHR
NHSE
Pre-Cinical
PHASE
I
PHASE
II
PHASE
III
PHASE
IV
The aim of this research is to trial two novel cannabinoid medicines; MRX2 (CBD) and MRX2T (CBD in combination with THC), to determine whether they are effective and safe in a broad range of seizure types and epilepsies in children and adults.
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ACTiON Study : Chemotherapy Induced Peripheral Neuropathy (CIPN)

CIPN
CBD for CIPN
CBD for Chemotherapy Pain
Pre-Cinical
PHASE
I
PHASE
II
PHASE
III
PHASE
IV
ACTiON is a Phase 2, double blind placebo-controlled crossover randomised clinical trial (‘RCT’) to assess Ananda’s patent-pending MRX1 drug candidate versus placebo in the treatment of CIPN.
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ENDOCAN-1: A Pilot Randomised Controlled Trial of the Efficacy of a CBD Oral Tincture in The Mangement of Endometriosis-Associated Pain

Endo
Endometriosis
Endowarrior
CBD for Endometriosis
Endometriosis Pain
Pre-Cinical
PHASE
I
PHASE
II
PHASE
III
PHASE
IV
ENDOCAN-1 will investigate if a future large scale, UK-wide trial to determine whether a cannabinoid can reduce endometriosis-associated pain is possible. 100 women with pelvic pain due to endometriosis will be randomly assigned to take MRX1 CBD drug candidate or identical placebo for 12 weeks.
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MRXBR02 Cardiac Fibrosis (Heart Failure with preserved Ejection Fraction or ‘HFpEF’)

HFpEF
Cardiac Fibrosis
Heart Failure
Heart Inflammation
Cardiac Function
Pre-Cinical
PHASE
I
PHASE
II
PHASE
III
PHASE
IV
HFpEF is a study designed to evaluate the cardioprotective effects of Ananda’s MRX1 drug candidate in a preclinical HFpEF model. The first part of the study was completed in June 2024.
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Our Approach

Transforming Lives Through Cannabinoid Medicines

We believe that cannabidiol, with its multiple molecular and cellular mechanisms of action has the potential to become a crucial element in the treatment plans for many complex conditions, especially in chronic pain and inflammatory indications.

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